LEVEL 5 Complete Guide to Peptides
KAIAN R&D Team |
Next-gen technologies overcome linear peptide limitations.
SPPS vs Recombinant
SPPS: high purity for short-chain. Recombinant: mass production for long-chain.
Cyclic & Stapled Peptides
Cyclic: ring structure for protease resistance. Stapled: locked helix for stability and permeability.
CPP & Exosome DDS
Cell-penetrating peptides for intracellular delivery. Exosomes as natural nanocapsules for targeted transport.
Synthetic advantage
Defined structure, reproducibility, clear safety — superior to unstable natural growth factors.
References
Key peer-reviewed sources behind the scientific statements in this article.
- Walensky LD, Bird GH. Hydrocarbon-stapled peptides: principles, practice, and progress. J Med Chem. 2014;57(15):6275-6288. PubMed
- Derossi D, Joliot AH, Chassaing G, Prochiantz A. The third helix of the Antennapedia homeodomain translocates through biological membranes. J Biol Chem. 1994;269(14):10444-10450.
- Jumper J, Evans R, Pritzel A, et al. Highly accurate protein structure prediction with AlphaFold. Nature. 2021;596(7873):583-589.
This article is reference information about cosmetic ingredients and does not guarantee efficacy. Figures and test results vary by condition.