Panthenol Pro-Vitamin B5

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SoothingBarrierMoisturizing

INCI: Panthenol (Pro-Vitamin B5)

Effect

Moisturizing, barrier repair, anti-inflammatory

Mechanism

Converts to pantothenic acid → CoA precursor → Barrier lipid synthesis promotion

Typical concentration

0.5-5%

Onset

Moisturizing: immediate. Barrier repair: 1-2 weeks

Cautions

Extremely high safety profile

Evidence & references

Ebner et al. (2002) [PubMed]

Journal

Related Journal

Skin-Concern SolutionsFor Those with Sensitive Skin Who Can't Use Anything -- Understanding What "Irritation" Really Means Skin-Concern SolutionsFor Those Who Can't Feel Their Aging Skin Recovering -- The "Foundation" Your Skin Needs Aesthetic Medicine vs Home CareEssential home care during aesthetic medicine "downtime"Aesthetic Medicine vs Home CareOptimal protocol for aesthetic medicine + home care -- a Skin Longevity perspective Skin Longevity SeriesThe Invisible Dryness Under Air Conditioning — The Science of TEWL and Barrier Function Skin Longevity SeriesThe 3-Day Obon Reset ── A Concentrated Rest Protocol for Sun-Tired Skin Skin Longevity SeriesThe Season-Change Switch: How the Autonomic Nervous System and the Skin Barrier Move Together Skin Longevity SeriesThe 4-Week Summer Damage Recovery Blueprint Skin Longevity SeriesRe-examining the "28-Day Turnover" Myth Through Science Skin Longevity SeriesIs PDRN (Salmon DNA) the Real Deal? Grading Regenerative Buzz Ingredients with Science

This page is reference information and does not guarantee efficacy. Figures vary by test conditions (in vitro / manufacturer / concentration). It does not indicate pharmaceutical efficacy.

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