Moisturizing

Serine

moisture-layer-design

MoisturizingBarrier

INCI: Serine

Effect

An amino acid that replenishes the natural moisturizing factor of the stratum corneum and imparts a moist feel

Mechanism

A major constituent amino acid of NMF. Having a hydroxyl group, it contributes to moisture absorption and retention and helps maintain stratum corneum hydration

Typical concentration

Roughly 0.05–1% (varies by product)

Onset

Moisturizing feel immediately after application

Cautions

Generally low-irritation

Evidence & references

https://pubchem.ncbi.nlm.nih.gov/compound/5951

Journal

Related Journal

Skin-Concern SolutionsFor Those Who Feel Cream Alone Isn't Enough -- What Needs to Happen Before You "Seal"The World of Fermented IngredientsSkin microbiome and fermented ingredients — how they interact Skin Longevity CarePracticing Skin Longevity with ingredients—morning and night routines How to Choose a SerumThe ingredient list: what the order really tells you The Truth Behind INCI LabelsThe front of the package is advertising; the back is the truth Seasonal & Environmental SkincareWinter skincare — protecting your barrier in a 30% humidity world Skin Longevity SeriesThe Lens of Evidence Concentration — The Line Between "Contains" and "Works"Skin Longevity SeriesThe Invisible Dryness Under Air Conditioning — The Science of TEWL and Barrier Function Skin Longevity SeriesCeramide, the Protagonist — The Science of the Lipid That Binds the Skin Skin Longevity SeriesDesigning Moisture in Layers — Humectant, Occlusive, Emollient

This page is reference information and does not guarantee efficacy. Figures vary by test conditions (in vitro / manufacturer / concentration). It does not indicate pharmaceutical efficacy.

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